Science with Purpose.
Work with Impact.
At MediWound, we are pioneering next-generation enzymatic therapies that transform the science of wound care. Our people are the foundation of our innovation — passionate scientists, clinicians, and professionals committed to advancing patient care through biotechnology.
As a global biotech company, MediWound offers opportunities to grow across research and development, clinical operations, manufacturing, regulatory affairs, and corporate functions. Here, your work will contribute to breakthrough therapies that improve outcomes for patients worldwide.
This is more than a career — it’s a chance to shape the future of regenerative healing.
Explore our opportunities and take the next step in your biotechnology journey with MediWound.
Open Positions
Validation Expert
We are looking for a Validation Manager who is responsible for hands-on management and execution of all validation and calibration activities at the manufacturing site. This is a highly hands-on role that involves direct execution of validation activities in the field, authoring and approving validation documentation, close daily interaction with production, labs and engineering teams, and professional management of external contractors and vendors. The role requires high independence, strong ownership, and end-to-end responsibility, from planning through execution and final reporting.
Hands-On Validation Execution
- Plan, execute, and approve validation activities for equipment, systems, and manufacturing processes.
- Perform hands-on IQ/OQ/PQ activities on the manufacturing floor.
- Validate:
- Manufacturing and packaging equipment.
- Utilities (HVAC, water systems, compressed air, gases).
- Cleanrooms.
- Lab equipment.
- Computerized systems (CSV – as applicable).
- Support equipment installation, FAT / SAT, and introduction of new equipment.
Documentation and Compliance
- Hands-on authoring of:
- Validation protocols.
- Validation reports.
- Risk assessments (FMEA).
- SOPs.
- Review and approve validation and quality documentation.
- Own, maintain, and update the Validation Master Plan (VMP).
Shop Floor & Manufacturing Support
- High level of presence on the manufacturing floor.
- Ongoing support to production during changes, deviations, and troubleshooting.
- Analysis of processes, yields, and statistical data.
- Support technology transfer and New Product Introduction (NPI) from development to commercial manufacturing.
Contractors and Vendors Management
- Hands-on professional management of validation and calibration contractors.
- Direct interaction with equipment suppliers, service providers, and external laboratories.
- Review and control of contractors’ execution quality and deliverables.
Quality & Regulatory Activities
- Manage deviations, investigations, and CAPAs related to validation.
- Lead Change Controls associated with equipment and processes.
- Prepare for and actively participate in regulatory inspections (FDA, EMA, internal audits).
- BSc in Engineering, Life Sciences, or a related field – mandatory.
- Minimum of 5 years of hands-on validation experience in a GMP environment – mandatory.
- Proven experience performing validations directly (not only managing).
- Strong knowledge of GMP and pharmaceutical regulatory requirements.
- Full understanding of the validation lifecycle.
- Experience with manufacturing equipment, utilities, and production systems.
- Strong hands-on mentality and willingness to execute independently.
- High level of initiative, ownership, and accountability.
- Ability to work independently in a fast-paced, multi-task environment.
- Excellent interpersonal and cross-functional communication skills.
- English – high level of reading and writing (mandatory).
- Hebrew – high level.
Come work with us
Validation Expert
JB-246
Pharmaceutical R&D Scientist
MediWound is seeking a motivated and scientifically driven Pharmaceutical and nonclinical development project manager to join our Pharmaceutical and nonclinical R&D team and contribute to multidisciplinary pharmaceutical development activities. The role spans multiple areas, including scientific studies, development of new drug product formulations and manufacturing processes, sterilization-related activities, and development and validation of new methods.
The position combines hands-on scientific work with study planning, data analysis, scientific documentation, collaboration with external CROs, and coordination with internal functions. The development activities span from early concept and formulation through CMC development for clinical trials, continued support throughout clinical development, and preparation for product approval. The successful candidate will contribute to moving development projects from scientific questions through execution, interpretation, and reporting, in accordance with project timelines and relevant regulatory requirements. The role includes project management responsibilities and does not involve direct management of a team.
- Design and execute experiments related to formulation and process development, scientific and biochemical studies, method development, and GMP validation activities.
- Prepare study plans and protocols based on regulatory guidelines, scientific knowledge, literature review, project objectives, timelines, and budget.
- Perform hands-on laboratory work, including formulation preparations and aseptic work.
- Develop, qualify, and validate new methods and processes in accordance with relevant regulatory guidelines and project needs.
- Process, analyze, interpret, and present scientific data; maintain complete raw-data records and write clear protocols, reports, and development documentation.
- Identify scientific and operational challenges, troubleshoot issues, and support the improvement of processes and methods.
- Coordinate activities with external CROs and service providers, including scope definition, progress follow-up, performance monitoring, and review of results, as applicable.
- Collaborate with internal interfaces, including Analytical R&D, Operations, QA, and Regulatory Affairs, to advance project activities and deliverables.
- Support regulatory activities and submissions related to pharmaceutical and nonclinical development projects.
- Manage priorities and multiple scientific activities in parallel while meeting agreed timelines.
- Ph.D. in Chemistry, Biochemistry, Pharmacology, Biotechnology, Biotechnology Engineering, or a related scientific field with at least 3 years R&D experience in the pharmaceutical or biotechnology industry, or M.Sc with at least 6 years R&D experience in the pharmaceutical or biotechnology industry
- Experience leading scientific and pharmaceutical development projects, formulation development or manufacturing-process development, preferably at clinical or commercial stages.
- Knowledge of pharmaceutical development guidelines, including GMP, GLP, and ICH, and familiarity with process and method validation principles.
- Experience working with and managing CROs or other external service providers.
- Strong scientific orientation and problem-solving ability, with the capacity to learn and work across different scientific disciplines.
- Strong organizational skills, attention to detail, and the ability to manage several activities in parallel.
- Excellent scientific writing, communication, and interpersonal skills.
- Self-motivated, collaborative, and able to work independently in a dynamic environment.
- Fluent English, spoken and written.
Advantages
- Experience with aseptic techniques and biochemical or enzymatic assays.
- Experience with biologically derived or enzyme-based products.
- Experience with sterile drug products, sterilization of excipients or raw materials, packaging development, or Container Closure Integrity Testing.
- Experience with Design of Experiments and statistical data analysis.
Come work with us
Pharmaceutical R&D Scientist
JB-242
Maintenance Technician
MediWound is seeking a Maintenance Technician to join our Maintenance Department at our manufacturing site in Yavne. This role is suited for a hands-on technician who is looking to develop professionally, expand technical expertise, and grow within a pharmaceutical organization over time.
- Perform routine maintenance of clean rooms, laboratories, and office areas.
- Maintain and operate equipment and machinery in a pharmaceutical manufacturing environment.
- Work with infrastructure systems including HVAC, water systems (RO/WFI), electrical and control systems, and refrigeration.
- Troubleshoot technical issues and perform corrective and preventive maintenance
- Work both independently and as part of a professional team.
- Take ownership of assigned tasks and drive them through completion.
- Work in compliance with Good Manufacturing Practice procedures and quality standards.
- At least 2 years of proven experience in maintenance work within clean rooms under GMP conditions.
- At least 2 years of experience working with systems and processes in pharmaceutical manufacturing facilities.
- Hands-on experience in at least one of the following areas:
- Mechanical systems/machinery
- HVAC and clean room systems
- Water systems (RO/WFI)
- Electrical and control systems
- Refrigeration systems.
- Ability to work independently and take ownership of tasks.
- Strong teamwork and collaboration skills.
- Proficiency in computerized work environments.
- Native level / fluent Hebrew.
- Good English skills.
- Certified electrician license – an advantage.
- Working-at-height certification – an advantage.
Additional Information:
The position includes on-call duty, shared among all team members.
Come work with us
Maintenance Technician
JB-235
Process & system Engineer
MediWound is seeking an experienced and highly motivated Process and System Engineer to join our MS&T team.
This role is responsible for supporting, improving, and scaling biopharmaceutical manufacturing processes, with a strong focus on technology transfer, process scale-up, engineering support, validation activities, and continuous process improvement. The position requires a hands-on engineering approach, a strong understanding of GMP production environments, and the ability to work cross-functionally with Engineering, Validation, Quality, Manufacturing, and external subcontractors.
The ideal candidate will bring significant experience in pharmaceutical or biopharmaceutical manufacturing, process engineering, and regulated environments, and will play a key role in ensuring robust, scalable, compliant, and continuously improving manufacturing processes.
Process support
- Responsible for Tech Transfer and scale-up of the production process, including exploring new technologies to enable efficient and robust scale up, data preservation, protocol writing and process improvements
- Writing all tech transfer documentation, protocols, reports, gap analysis according to relevant guidelines
- Responsible for supporting and setting the policy and actual implementation of all processes and engineering aspects including constant improvement of existing and new processes.
- Develop robust process control strategies, including automation and advanced analytics, to enhance manufacturing consistency and scalability.
- Accompanying and supporting the planning and execution of validation for processes and equipment under the department’s responsibility.
- Responsible for the initiation and execution of change requests, deviations, and corrective actions in accordance with the procedures and quality systems of the company.
- Work closely with the engineering & validation department, also engineering subcontractor company to ensure that engineering projects are completed on time and within allocated resources.
- Lead and apply advanced engineering principles to optimize biopharmaceutical manufacturing processes, including UF process, lyophilization procedures and fill-finish operations.
- Utilize engineering methodologies (e.g., process modeling, data analysis, control systems design) to ensure scalable, efficient, and cost-effective production.
- Ensure that all engineering and process design work complies with relevant regulatory standards (FDA, EMA, ICH) and cGMP guidelines, maintaining a state of readiness for audits and inspections.
Education
- Bachelor’s, Master’s, or PhD in Chemical Engineering, Biochemical Engineering, Mechanical Engineering, or a related engineering field.
Experience
- Minimum of 7 years of experience in biopharmaceutical or pharmaceutical manufacturing, focusing on process engineering with hands on familiarity with cleanrooms and GMP production areas.
- Significant experience in managing complex engineering projects within regulated environments (FDA, EMA).
- Advantage to experience with aseptic processing, powder handling, and isolator technology.
Skills
- Expertise in engineering aspects of biopharmaceutical manufacturing, including scaled down and fill &finish process and equipment, such as lyophilizer, UF and isolator.
- Proficiency in process development, scale-up, optimization, and validation for commercial products.
- Deep knowledge of regulatory requirements (FDA, EMA) and cGMP standards as applied to engineering design and process operations.
- Previous experience in leading tech transfer of production process in the pharma industry or equivalent.
- Strong communication skills, with the ability to collaborate across functions and present complex engineering concepts to non-technical stakeholders.
- Strategic and analytical thinker with strong problem-solving skills and a hands-on practice approach