Advancing Bromelain-Based Novel Therapies
for Better Standard of Care
Our capabilities are well demonstrated in our diversified products and pipeline.
NexoBrid, our commercial orphan biological product for eschar removal of severe thermal burns, is a bromelain-based biological product, containing a sterile mixture of proteolytic enzymes that selectively removes burn eschar within four hours and does not harm surrounding viable tissue. Nexobrid is currently marketed in the European Union as well as in other international markets and is at a registration stage in the U.S. NexoBrid is supported by the U.S. Biomedical Advanced Research and Development Authority (BARDA).
EscharEx, our next-generation bioactive therapy for debridement of chronic and hard-to-heal wounds, is a product candidate in advanced stages of clinical development. In two Phase 2 studies, EscharEx was well-tolerated and has demonstrated safety and efficacy in the debridement of various chronic and other hard-to-heal wounds, with only a few daily applications.
MW005, our topical enzymatic therapy for the treatment of non-melanoma skin cancers, is a clinical-stage product candidate under development.
NexoBrid® Eschar removal of deep partial and full thickness burns
Registration Stage in the U.S.
NEXT Expanded access treatment protocol
CIDS Pediatric phase 3 study
EscharEx® Debridement of chronic wounds
ChornEx U.S. Phase 2 adaptive design study
PharmEx Phase 2 pharmacology study
MW005 Non-melanoma skin cancer
Phase I/II study in BCC